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Improvement of heart rate variability after exercise training and its predictors in COPD.
MedLine Citation:
PMID:  21342757     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Current literature lacks solid evidence on the improvement of heart rate variability (HRV) after exercise training in patients with COPD. OBJECTIVES: We aimed to investigate changes in HRV after two exercise training programs in patients with COPD and to investigate the determinants of these eventual changes. METHODS: Forty patients with COPD (FEV(1) 39±13%pred) were randomized into high (n=20) or low (n=20) intensity exercise training (3-month duration), and had their HRV assessed by the head-up tilt test before and after either protocols. Baseline spirometry, level of daily physical activity, exercise capacity, body composition, functional status, health-related quality of life and muscle force were also assessed to investigate the determinants of improvement in HRV after the training program. RESULTS: There was a significant improvement in HRV only after the high-intensity protocol (pre versus post; SDNN 29±15ms versus 36±19ms; rMSSD 22±14ms versus 28±22ms; p<0.05 for both). Higher values of biceps brachialis strength, time spent walking in daily life and SDNN at baseline were determinants of improvement in HRV after the training program. CONCLUSIONS: High-intensity exercise training improves HRV at rest and during orthostatic stimulus in patients with COPD. Better baseline total HRV, muscle force and daily physical activity level are predictors of HRV improvements after the training program.
Authors:
Carlos Augusto Camillo; Viviane de Moraes Laburu; Nicole Soriano Gonçalves; Vinícius Cavalheri; Fernanda Priore Tomasi; Nidia Aparecida Hernandes; Dionei Ramos; Luiz Carlos Marquez Vanderlei; Ercy Mara Cipulo Ramos; Vanessa Suziane Probst; Fabio Pitta
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-20
Journal Detail:
Title:  Respiratory medicine     Volume:  -     ISSN:  1532-3064     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908438     Medline TA:  Respir Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Laboratório de Pesquisa em Fisioterapia Pulmonar (LFIP), Departamento de Fisioterapia, Universidade Estadual de Londrina (UEL), Londrina, Paraná, Brazil; Programa de Mestrado em Fisioterapia, Departamento de Fisioterapia, UNESP - Univ Estadual Paulista, Presidente Prudente, São Paulo, Brazil.
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