| Improvement of action myoclonus by an administration of 5-hydroxytryptophan and carbidopa in a child with muscular subsarcolemmal hyperactivity. | |
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MedLine Citation:
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PMID: 2288384 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a 3-year-11-month-old boy who manifested action myoclonus only. Histochemical analysis of the quadriceps muscle revealed subsarcolemmal hyperactivity. The administration of 5-hydroxytryptophan and carbidopa dramatically improved the action myoclonus and reduced an amplitude of giant somatosensory evoked potentials. A nosological relation of this case with "essential myoclonus" and mitochondrial encephalomyopathy was discussed. |
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Authors:
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K Nakano; T Hayakawa; K Shishikura; M Ohsawa; H Suzuki; Y Fukuyama |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Brain & development Volume: 12 ISSN: 0387-7604 ISO Abbreviation: Brain Dev. Publication Date: 1990 |
Date Detail:
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Created Date: 1991-03-22 Completed Date: 1991-03-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7909235 Medline TA: Brain Dev Country: JAPAN |
Other Details:
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Languages: eng Pagination: 516-20 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Tokyo Women's Medical College, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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5-Hydroxytryptophan
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therapeutic use* Carbidopa / therapeutic use* Child, Preschool Humans Male Muscles / pathology, ultrastructure Muscular Diseases / complications, drug therapy*, pathology Myoclonus / drug therapy*, etiology |
| Chemical | |
Reg. No./Substance:
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38821-49-7/Carbidopa; 56-69-9/5-Hydroxytryptophan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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