Document Detail


Improvement of acquired pendular nystagmus by gabapentin: case report.
MedLine Citation:
PMID:  12455139     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acquired Pendular Nystagmus (APN) may cause distressing visual symptoms in patients who are already suffering a severe general disease. Averbuch-Heller et al. conducted the first double-blind controlled study on treatment for APN. They showed that gabapentin substantially reduces pendular nystagmus and significantly increases visual acuity in the majority of patients. We present a patient with APN due to multiple sclerosis who suffered severe oscillopsy and reduction of visual acuity and who substantially benefited from a trial treatment with this agent.
Authors:
K Fabre; H Smet-Dieleman; T Zeyen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Bulletin de la Société belge d'ophtalmologie     Volume:  -     ISSN:  0081-0746     ISO Abbreviation:  Bull Soc Belge Ophtalmol     Publication Date:  2001  
Date Detail:
Created Date:  2002-11-28     Completed Date:  2003-02-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505353     Medline TA:  Bull Soc Belge Ophtalmol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  43-6     Citation Subset:  IM    
Affiliation:
Dienst Oogheelkunde, A.Z. Middelheim, Antwerpen.
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MeSH Terms
Descriptor/Qualifier:
Acetic Acids / therapeutic use*
Administration, Oral
Amines*
Baclofen / administration & dosage
Cyclohexanecarboxylic Acids*
Female
Humans
Middle Aged
Multiple Sclerosis / complications*
Nystagmus, Pathologic / drug therapy*,  etiology
Treatment Outcome
gamma-Aminobutyric Acid*
Chemical
Reg. No./Substance:
0/Acetic Acids; 0/Amines; 0/Cyclohexanecarboxylic Acids; 1134-47-0/Baclofen; 56-12-2/gamma-Aminobutyric Acid; 60142-96-3/gabapentin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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