| Improvement of IVF results and optimisation of quality control by using intermittent activity. | |
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MedLine Citation:
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PMID: 15588470 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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For several years the present authors' team had not been satisfied with the pregnancy rate achieved by their unit, especially in comparison with the results achieved by other teams with a similar population. A quality programme was established, and it was decided to switch from non-stop to intermittent activity. It was envisaged that this programme would provide a more realistic view of the team's activity and could also, as a secondary effect, improve its results. The team's experience of an in-series organization was presented for the management of 408 consecutive infertile couples, during 2002. The results obtained during 2002 were compared with those for two previous years. There was a significant increase (P < 0.01) in the clinical pregnancy rate per oocyte retrieval from 28.9% (2000) and 25.2% (2001) to 41% (2002) in IVF and from 23% (2000) and 26% (2001) to 38.5% (2002) in intracytoplasmic sperm injection (ICSI). A significant increase (P < 0.01) was also observed in the implantation rate, from 14.8% and 13.4% to 20% in IVF and from 12.1% and 12.9% to 23.5% in ICSI. The higher pregnancy rate was achieved without an increase in the multiple pregnancy rate. In conclusion, recent data support the hypothesis that the use of a quality management system, can, as in this case, have positive repercussions on pregnancy rates. |
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Authors:
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Nelly Frydman; Rénato Fanchin; Anne Le Dû; Marie Catherine Bourrier; Gérard Tachdjian; René Frydman |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 9 ISSN: 1472-6483 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2004-12-13 Completed Date: 2005-03-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: England |
Other Details:
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Languages: eng Pagination: 521-8 Citation Subset: IM |
Affiliation:
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Service de Génétique et Reproduction, Hôpital Antoine Béclère, 157 rue de la porte de Trivaux 92140 Clamart, France. nelly.frydman@abc.ap-hop-paris.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Embryo Transfer Female Fertilization in Vitro / standards* Humans Oocytes Pregnancy Pregnancy Rate Quality Assurance, Health Care* Quality Control* Reproductive Medicine / standards* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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