Document Detail


Improved wound management by regulated negative pressure-assisted wound therapy and regulated, oxygen- enriched negative pressure-assisted wound therapy through basic science research and clinical assessment.
MedLine Citation:
PMID:  23162229     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Regulated negative pressure-assisted wound therapy (RNPT) should be regarded as a state-of-the-art technology in wound treatment and the most important physical, nonpharmaceutical, platform technology developed and applied for wound healing in the last two decades. RNPT systems maintain the treated wound's environment as a semi-closed, semi-isolated system applying external physical stimulations to the wound, leading to biological and biochemical effects, with the potential to substantially influence wound-host interactions, and when properly applied may enhance wound healing. RNPT is a simple, safe, and affordable tool that can be utilized in a wide range of acute and chronic conditions, with reduced need for complicated surgical procedures, and antibiotic treatment. This technology has been shown to be effective and safe, saving limbs and lives on a global scale. Regulated, oxygen-enriched negative pressure-assisted wound therapy (RO-NPT) is an innovative technology, whereby supplemental oxygen is concurrently administered with RNPT for their synergistic effect on treatment and prophylaxis of anaerobic wound infection and promotion of wound healing. Understanding the basic science, modes of operation and the associated risks of these technologies through their fundamental clinical mechanisms is the main objective of this review.
Authors:
Moris Topaz
Related Documents :
11742169 - Effects of magnetic sacral root stimulation on anorectal pressure and volume.
3653529 - Effect of cisapride on the gastro-oesophageal function in normal human subjects.
8769279 - Effects of intraduodenal air insufflation on sphincter of oddi motility in conscious dogs.
11077329 - Antral compensation after proximal gastric vagotomy.
12378649 - Study on the function of pharynx upper esophageal sphincter in globus hystericus.
14731129 - Visceral perception thresholds after rectal thermal and pressure stimuli in irritable b...
10589889 - Fluid replacement in dengue shock syndrome: a randomized, double-blind comparison of fo...
22848069 - Excessive wave reflections on admission predict post-discharge events in patients hospi...
25351429 - Inflammatory optic disc edema due to sarcoidosis mimicking malignant hypertension.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India     Volume:  45     ISSN:  1998-376X     ISO Abbreviation:  Indian J Plast Surg     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-11-19     Completed Date:  2012-11-20     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  8405356     Medline TA:  Indian J Plast Surg     Country:  India    
Other Details:
Languages:  eng     Pagination:  291-301     Citation Subset:  -    
Affiliation:
Plastic Surgery Unit, Hillel Yaffe Medical Center, Hadera, Department of Chemistry, Bar Ilan University, Ramat Gan, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Wound coverage considerations for defects of the lower third of the leg.
Next Document:  Exploiting potency of negative pressure in wound dressing using limited access dressing and suction-...