Document Detail

Improved survival and neurodevelopmental outcome for infants less than 801 grams birthweight.
MedLine Citation:
PMID:  2331279     Owner:  NLM     Status:  MEDLINE    
We reviewed the perinatal management and subsequent outcome of infants 401 to 800 gm birthweight delivered in 1983 to 1985 compared with those born in 1980 to 1982. Intrapartum fetal heart rate monitoring, cesarean section delivery, attempted delivery room resuscitation, and 5-minute Apgar scores greater than 5 were more frequent in 1983 to 1985. Significantly greater neonatal survival was evident for infants 500 to 700 gm birthweight (31%) and 24 to 27 weeks' gestation (45%) in 1983 to 1985, p less than 0.005. Infant birthweight, gestational age, gender, and 5-minute Apgar score, in addition to intrapartum tocolysis use, were predictors of higher survival by stepwise discriminant analysis. At a mean follow-up of 27 months, 13% (6 of 46) born in 1983 to 1985 had major disability compared with 67% (6 of 9) of infants born in 1980 to 1982. There has been a significant increase in survival and improvement in neurodevelopmental follow-up status for infants less than 801 gm birthweight. These improved outcome data should be considered by caregivers providing perinatal management and counseling parents regarding extremely low birthweight infants.
H W Kilbride; D K Daily; K Claflin; R T Hall; D Maulik; H O Grundy
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of perinatology     Volume:  7     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-06-06     Completed Date:  1990-06-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  160-5     Citation Subset:  IM    
Department of Pediatrics, Children's Mercy Hospital, Kansas City, Missouri 64108.
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MeSH Terms
Apgar Score
Birth Weight
Gestational Age
Heart Rate, Fetal
Infant Mortality*
Infant, Low Birth Weight
Infant, Newborn
Nervous System Malformations*
Pregnancy Outcome / epidemiology*
Prenatal Care

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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