Document Detail

Improved respiratory prognosis in patients with cystic fibrosis with normal fat absorption.
MedLine Citation:
PMID:  7086584     Owner:  NLM     Status:  MEDLINE    
The clinical presentation, courses, and sweat chloride values of 72 CF patients with normal fat absorption are described. In general, these patients had milder clinical symptoms and a lower mean sweat chloride value than their counterparts with steatorrhoea. Pulmonary function tests, including FEV1, FVC, FEF25%-75%, PaO2, and RV/TLC%, were significantly better in patients with normal fat absorption compared with both male and female patients who had steatorrhoea. The maintenance of better pulmonary function, coupled with the low mortality, suggests that patients without steatorrhoea have a better prognosis. This difference remains unexplained, but may be contributed to by nutritional, genetic, or pancreatic factors.
K Gaskin; D Gurwitz; P Durie; M Corey; H Levison; G Forstner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  100     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1982 Jun 
Date Detail:
Created Date:  1982-08-26     Completed Date:  1982-08-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  857-62     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Chlorides / analysis
Cystic Fibrosis / metabolism,  physiopathology*
Dietary Fats / metabolism*
Intestinal Absorption
Pancreas / physiopathology
Respiratory Function Tests
Sex Factors
Sweat / analysis
Reg. No./Substance:
0/Chlorides; 0/Dietary Fats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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