| Improved myocardial protection by antegrade perfusion in combination with coronary sinus occlusion in the presence of left anterior descending artery obstruction. | |
| | |
MedLine Citation:
|
PMID: 8326529 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The present study was undertaken to evaluate the improved protection of antegrade aortic root perfusion combined with intermittent coronary sinus occlusion (APCSO) for the 1-hour ischemic myocardium in the presence of left anterior descending artery occlusion, 12 dogs were divided into 2 groups: anteperfusion (AP) alone (n = 6) and APCSO (n = 6). The experimental results showed that APCSO provided a better cardioplegic distribution and a lower hypothermia (15.6 degrees C versus 17.2 degrees C) in the occluded LAD region, compared with AP. After ischemia, cardiac index and left ventricular stroke index recovered excellently in APCSO (128% to 141% and 115% to 158% of preischemic values, respectively), and much worse in AP (69% to 82% and 53% to 73% of preischemic values, respectively). Our study has confirmed that APCSO is superior to AP in myocardial protection in the presence of coronary artery occlusion. |
| | |
Authors:
|
X P Fu; K J Zhang; S D Ye; N G Dong; Y M Shao; Z J Xu; H J Lan |
Related Documents
:
|
6974579 - 'currents and clots'--an approach to the problem of acute variceal bleeding. 22355489 - Triple vessel coronary artery disease presenting as a markedly positive stress electroc... 6236249 - Influence of acute arterial hypertension on myocardial infarct size in dogs without lef... 8587349 - Ventricular tachycardias induced by intracoronary administration of endothelin-1 in dogs. 3425739 - The iron chelator desferrioxamine attenuates postischemic ventricular dysfunction. 10598899 - Development and evaluation of a new canine myocardial infarction model using a closed-c... 21606749 - Contribution of fetal tricuspid regurgitation in first-trimester screening for major ca... 17867629 - Pre-ischemic administration of landiolol prevents ischemia-reperfusion injury in the ra... 22800819 - Incidence and predictors of definite stent thrombosis after coronary stent implantation. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of Tongji Medical University = Tong ji yi ke da xue xue bao Volume: 13 ISSN: 0257-716X ISO Abbreviation: J. Tongji Med. Univ. Publication Date: 1993 |
Date Detail:
|
Created Date: 1993-08-06 Completed Date: 1993-08-06 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 8605495 Medline TA: J Tongji Med Univ Country: CHINA |
Other Details:
|
Languages: eng Pagination: 45-50 Citation Subset: IM |
Affiliation:
|
Department of Cardiovascular Surgery, Tongji Medical University, Wuhan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cardioplegic Solutions / pharmacology* Cardiopulmonary Bypass Coronary Vessels / surgery Dogs Heart Arrest, Induced / methods* Myocardial Reperfusion / methods* Myocardial Reperfusion Injury / prevention & control |
| Chemical | |
Reg. No./Substance:
|
0/Cardioplegic Solutions |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of thymosin on the secretion of the sexual hormone in rats with experimental varicocele.
Next Document: A dual fiber-optic sensor for oxygen and carbon dioxide.