| Improved long-term survival following complete eradication of esophageal varices by sclerotherapy. | |
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MedLine Citation:
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PMID: 10228784 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIMS: Conflicting results have been reported concerning the effect of endoscopic injection sclerotherapy upon the long-term survival of cirrhotic patients with esophageal varix. The recurrence and rebleeding of esophageal varices seems to be an important factor influencing long-term survival. We investigated the long-term survival of patients after complete eradication of esophageal varices. METHODOLOGY: Forty patients treated by endoscopic injection sclerotherapy for acute esophageal variceal bleeding were studied. The recurrence rate of varices and the long-term survival of patients in whom complete eradication of esophageal varices was obtained were compared with those of patients in whom the eradication of varices was incomplete. RESULTS: The frequency of the recurrence/deterioration rate of varices and rebleeding in the complete eradication group was significantly lower than that in the incomplete eradication group (10.7% vs. 100%, 0% vs. 58.3%, respectively, p < 0.01). Accumulated 5-year survival rate of the complete eradication group was significantly higher than that of the incomplete eradication group (68.2% vs. 43.2%, p < 0.05). CONCLUSIONS: Complete eradication of esophageal varices by endoscopic injection sclerotherapy is effective both in preventing variceal re-bleeding and in improving the survival of cirrhotic patients with esophageal varices. |
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Authors:
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H Matsumoto; F Suzuki; K Souda; H Kitahara; Y Kobayashi; T Kawasaki; K Nakao; M Matsumoto; K Iwata; Y Ohta; K Kanai |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 46 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 1999 Jan-Feb |
Date Detail:
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Created Date: 1999-06-23 Completed Date: 1999-06-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: GREECE |
Other Details:
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Languages: eng Pagination: 172-6 Citation Subset: IM |
Affiliation:
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Department of Gastroenterology, Toshiba General Hospital, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Aged Aged, 80 and over Esophageal and Gastric Varices / mortality*, therapy* Female Humans Male Middle Aged Recurrence Sclerotherapy* Survival Analysis Treatment Outcome |
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