Document Detail


Improved identification of the palmar fibrocartilage of the navicular bone with saline magnetic resonance bursography.
MedLine Citation:
PMID:  19999343     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fibrocartilage degeneration is the earliest pathologic finding in navicular disease but remains difficult to detect, even with magnetic resonance (MR) imaging. We hypothesized that injection of the navicular bursa with saline would improve accuracy of MR imaging evaluation of palmar fibrocartilage. Thoracic limbs were collected from 11 horses within 6 h of death. Imaging was performed with a 1.5 T magnet using sagittal 2D proton density and transverse 3D FLASH sequences with fat saturation. For the purpose of determining sensitivity and specificity of the MR images, fibrocartilage was classified as normal or abnormal, based on combination of the findings of gross and microscopic pathology. Thickness of fibrocartilage was measured on histologic sections and corresponding transverse FLASH MR images before and after injection of saline. A paired Student's t-test was used for comparison of measurements. Partial thickness fibrocartilage loss was present in 6 of 22 limbs. Sensitivity of precontrast MR images for detection of lesions was 100% while specificity was 6%. Saline MR arthrography resulted in both sensitivity and specificity of 100% based on consensus review. Mean histologic fibrocartilage thickness was 0.75 +/- 0.12 mm. Mean fibrocartilage thickness on precontrast transverse FLASH images was 0.93 +/- 0.065 and 0.73 +/- 0.09 mm on postsaline images. The histologic cartilage thickness was signficantly different from that in precontrast images (P<0.001) but not in images acquired after saline injection (P = 0.716). Based on our results, and using pulse sequences as described herein, navicular fibrocartilage can only be evaluated reliably for the presence of partial thickness lesions after intrabursal injection of saline.
Authors:
Michael Schramme; Zoltan Kerekes; Stuart Hunter; Krisztina Nagy; Anthony Pease
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association     Volume:  50     ISSN:  1058-8183     ISO Abbreviation:  Vet Radiol Ultrasound     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-12-14     Completed Date:  2010-04-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9209635     Medline TA:  Vet Radiol Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  606-14     Citation Subset:  IM    
Affiliation:
College of Veterinary Medicine, North Carolina State University, Hillsborough Street 4700, Raleigh, NC 27606, USA. michael_schramme@ncsu.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Ankle / radiography*
Contrast Media / administration & dosage
Euthanasia, Animal
Fibrocartilage / radiography*
Horse Diseases / diagnosis*
Horses
Imaging, Three-Dimensional / veterinary
Magnetic Resonance Imaging / methods,  veterinary*
Sensitivity and Specificity
Sodium Chloride / administration & dosage
Tarsus, Animal / radiography*
Chemical
Reg. No./Substance:
0/Contrast Media; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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