Document Detail

Improved food intake and reduced nausea and vomiting in patients given a restricted diet while receiving cisplatin chemotherapy.
MedLine Citation:
PMID:  1728624     Owner:  NLM     Status:  MEDLINE    
Administration of cisplatin alone or in combination with other cytotoxic agents commonly produces intractable nausea and vomiting, which is currently controlled through high-dose antiemetic drugs. However, patients often refuse continued therapy because of suboptimal control of nausea and vomiting and substantial decline in nutritional status. In this pilot study, 19 patients receiving cisplatin were evaluated for nausea and vomiting, amount of food intake, and subjective assessment of well-being. The study group received a colorless, odorless, predetermined meal three times daily; the meal included cottage cheese, apple sauce, vanilla ice cream, and other selected foods. Control-group patients selected their own meal. Study-group patients exhibited higher overall food intake, decreased nausea and vomiting, and a higher scored estimation of well-being. The findings of this preliminary study indicate that the study diet helps provide nutrition care to cancer patients receiving cisplatin chemotherapy and helps create an atmosphere where the patient believes he or she has some control in the treatment outcome.
L Menashian; M Flam; D Douglas-Paxton; J Raymond
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of the American Dietetic Association     Volume:  92     ISSN:  0002-8223     ISO Abbreviation:  J Am Diet Assoc     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-02-06     Completed Date:  1992-02-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503061     Medline TA:  J Am Diet Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  58-61     Citation Subset:  AIM; IM    
Corporate Cancer Services, Fresno Community Hospital and Medical Center, CA 93715.
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MeSH Terms
Aged, 80 and over
Cisplatin / adverse effects*
Energy Intake
Middle Aged
Nausea / chemically induced,  prevention & control*
Patient Satisfaction
Pilot Projects
Random Allocation
Vomiting / chemically induced,  prevention & control*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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