| Improved early ventricular performance with a right ventricle to pulmonary artery conduit in stage 1 palliation for hypoplastic left heart syndrome: evidence from strain Doppler echocardiography. | |
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MedLine Citation:
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PMID: 14729795 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To quantify non-invasively right ventricular (RV) performance in infants after stage 1 palliation for hypoplastic left heart syndrome (HLHS). DESIGN: Prospective, observational study with two dimensional and strain Doppler echocardiography. SETTING: Single tertiary paediatric cardiology centre. PATIENTS: Convenience sample of nine consecutive infants with HLHS. Four whose surgery involved a systemic to pulmonary artery (S-PA) shunt were compared with five whose surgery incorporated a right ventricle to pulmonary artery (RV-PA) conduit. METHODS: Basal RV free wall longitudinal strain rate, systolic strain (epsilon), and RV percentage area change were calculated during a single assessment between 27-50 days after surgery. RESULTS: Cardiopulmonary bypass time was longer in patients who underwent RV-PA (226 (30) minutes v 181 (18) minutes, p = 0.03), but cross clamp time, duration of ventilation, and inotrope use did not differ. Two patients in the S-PA group died, on days 29 and 60 after surgery. Peak systolic strain rate (-1.24 (0.19)/s v -0.91 (0.21)/s, p = 0.048), peak epsilon (-17.8 (1.8)% v -13.4 (2.0)%, p = 0.01), and RV percentage area change (56 (6)% v 25 (6)%, p < 0.01) were all greater among RV-PA patients. These indices also tended to be greater in survivors as a group. Ventricular loading conditions (oxygen saturations, diuretic treatment, and blood pressure) were similar in both groups. CONCLUSION: Strain Doppler echocardiography shows improved RV longitudinal systolic contractility in patients during convalescence after the RV-PA modification of stage 1 palliation for HLHS compared with those with an S-PA shunt. |
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Authors:
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M L Hughes; L S Shekerdemian; C P Brizard; D J Penny |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Heart (British Cardiac Society) Volume: 90 ISSN: 1468-201X ISO Abbreviation: Heart Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-01-19 Completed Date: 2004-02-19 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 9602087 Medline TA: Heart Country: England |
Other Details:
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Languages: eng Pagination: 191-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, Royal Children's Hospital, Melbourne, Australia. marina.hughes@rch.org.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anastomosis, Surgical Cardiopulmonary Bypass / methods Echocardiography, Doppler Female Heart Ventricles / surgery* Humans Hypoplastic Left Heart Syndrome / physiopathology, surgery*, ultrasonography Infant Infant, Newborn Male Palliative Care / methods Prospective Studies Pulmonary Artery / surgery* Ventricular Dysfunction, Right / physiopathology, surgery* |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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