| Improved diagnostic yield with severity of bleeding. | |
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MedLine Citation:
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PMID: 21955428 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: Video capsule endoscopy (VCE) is an important tool for non-invasive imaging of the small bowel. Whether there is a dose-related effect of anemia severity on the diagnostic yield of VCE is unknown. The aim of this study was to determine the influence of anemia severity on VCE outcome measures. METHODS: VCE studies from the Sacramento Veterans Affairs Medical Center for 300 consecutive patients were retrospectively screened. Those with anemia were selected. Patients were grouped as mildly, moderately or severely bleeding. Outcomes data including completion of study, diagnostic yield and further intervention were compared. RESULTS: Of the 300 patients, 210 (70%) were found to have anemia. Overall 32 (15.24%) patients were mildly, 145 (69.05%) were moderately and 33 (15.71%) were severely bleeding. The diagnostic yield was significantly higher in severe (72.73%) relative to moderate (32.41%) and mild bleeding (12.50%); P = 0.0001. Significantly more angioectasias were detected in severely bleeding patients (42.42%) than in those bleeding moderately (14.48%) and mildly (0.00%), P = 0.0001. The ability of VCE to guide further intervention was significantly higher in patients bleeding severely (69.70%, P = 0.006). CONCLUSIONS: Our data showed a significant increase in diagnostic yield with the increasing degree of anemia. Relative difference in hemoglobin rather than absolute values may be a better predictor. The ability of VCE to guide further intervention reached significance in severely bleeding patients. The hypothesis that use of VCE prior to esophagogastroduodenoscopy or colonoscopy in the severely bleeding group deserves to be evaluated. |
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Authors:
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Dhavan A Parikh; Mohit Mittal; Felix W Leung; Surinder K Mann |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of digestive diseases Volume: 12 ISSN: 1751-2980 ISO Abbreviation: J Dig Dis Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-09-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101302699 Medline TA: J Dig Dis Country: Australia |
Other Details:
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Languages: eng Pagination: 357-63 Citation Subset: IM |
Copyright Information:
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© 2011 The Authors. Journal of Digestive Diseases © 2011 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd. |
Affiliation:
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Department of Gastroenterology, UC Davis Medical Center, Sacramento UC Davis School of Medicine, Sacramento Department of Gastroenterology, Sepulveda ACC, VAGLAHS, North Hill and David Geffen School of Medicine at UCLA, Los Angeles Department of Gastroenterology, Sacramento Veteran Affairs Medical Center, VANCHCS, Mather, California, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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