| Improved detection and localization of lower gastrointestinal hemorrhage using subtraction scintigraphy: clinical evaluation. | |
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MedLine Citation:
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PMID: 17496006 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Does subtraction scintigraphy improve the diagnostic utility of scintigraphic evaluation in acute lower gastrointestinal hemorrhage? METHODS: This research was a retrospective clinical study using a repeat-measures design of randomized control and experimental groups. A single patient dataset provided both the control group (conventional scintigraphy) and the experimental group (conventional and subtraction techniques). Forty-nine raw (99m)Tc-red blood cell studies were randomized and interpreted by 4 independent physicians as conventional scintigraphy data only (round 1). The conventional scintigraphy studies were combined with subtraction images and randomized for reinterpretation (round 2). RESULTS: Although there was a decrease in the mean, no statistically significant difference was noted between the mean time to bleed detection between interpretive rounds 1 and 2 (P = 0.524). The addition of subtraction scintigraphy to the interpretation process changed the outcome from "probably present" to "absent" for 14% of patients and from "equivocal" to "absent" for another 12%, and this change had a marked effect on the false-positive rate. The false-positive rate decreased from 9.6% in round 1 to 3.6% in round 2. Receiver operator characteristic analysis showed that combining conventional scintigraphy with subtraction scintigraphy improved test performance. CONCLUSION: False-positive studies can be reduced by using subtraction scintigraphy in conjunction with conventional scintigraphy in the interpretive process. |
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Authors:
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Geoffrey M Currie; Philip A Towers; Janelle M Wheat |
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Publication Detail:
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Type: Journal Article Date: 2007-05-11 |
Journal Detail:
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Title: Journal of nuclear medicine technology Volume: 35 ISSN: 0091-4916 ISO Abbreviation: J Nucl Med Technol Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-05-31 Completed Date: 2007-08-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0430303 Medline TA: J Nucl Med Technol Country: United States |
Other Details:
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Languages: eng Pagination: 105-11 Citation Subset: IM |
Affiliation:
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School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, Australia. gcurrie@csu.edu.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Gastrointestinal Hemorrhage / radionuclide imaging* Humans Image Enhancement / methods* Image Interpretation, Computer-Assisted / methods* Male Middle Aged Reproducibility of Results Retrospective Studies Sensitivity and Specificity Subtraction Technique* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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