Document Detail

Improved cine MR imaging of left ventricular wall motion with gadopentetate dimeglumine.
MedLine Citation:
PMID:  8428079     Owner:  NLM     Status:  MEDLINE    
The assessment of left ventricular wall motion with cine magnetic resonance imaging in the cardiac long axes is useful; however, image quality is limited by reduced signal intensity due to saturation of blood flowing predominantly in plane. Twenty subjects were studied to evaluate the effects of gadopentetate dimeglumine on contrast between blood and myocardium. Contrast improved significantly on contrast agent-enhanced images in the long axes, at both end-systole (vertical axis, +62%, P < .0001; horizontal axis, +67%, P < .0001) and end-diastole (vertical axis, +50%, P < .0001; horizontal axis, +26%, P < .004). The increase in the short axis was less and significant only at end-systole (+25%, P < .0001). Subjective scoring of the cines also showed a significant and clinically useful improvement in the long axes (P < .0001 for both) on contrast-enhanced images. Improved contrast was most evident for 10 minutes after injection, but persisted for up to 20 minutes at end-systole in the long axes. Gadopentetate dimeglumine is useful for cine imaging of left ventricular wall motion when saturation effects prevent adequate clinical assessment.
D J Pennell; S R Underwood; D B Longmore
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  3     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:    1993 Jan-Feb
Date Detail:
Created Date:  1993-03-09     Completed Date:  1993-03-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  13-9     Citation Subset:  IM    
Magnetic Resonance Unit, Royal Brompton National Heart and Lung Hospitals, London, United Kingdom.
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MeSH Terms
Contrast Media
Gadolinium / diagnostic use*
Gadolinium DTPA
Image Enhancement / methods
Magnetic Resonance Imaging / methods*
Middle Aged
Myocardial Infarction / diagnosis
Myocardium / pathology*
Organometallic Compounds / diagnostic use*
Pentetic Acid / diagnostic use*
Ventricular Function, Left / physiology*
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 67-43-6/Pentetic Acid; 7440-54-2/Gadolinium; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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