| Improved bone mineral status in very low birthweight infants fed human milk mixed with preterm formula. | |
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MedLine Citation:
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PMID: 2504028 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The bone mineral status of very low birthweight (VLBW) infants fed exclusively their own mother's milk (group I) was compared with that of VLBW infants fed mother's milk in the initial 4 weeks followed by a 1:1 mixture of mother's milk and preterm formula containing high phosphorus (P) and calcium (Ca) (group II). In both groups, most infants showed a biochemical picture characteristic of phosphorus deficiency syndrome by the fourth week. Thereafter, serum alkaline phosphatase activity (ALP) decreased and serum P increased in all group II infants. Conversely, serum ALP rose and hypophosphatemia persisted in most group I infants. Group II had a significantly higher serum P at weeks 8 and 12 and a significantly lower ALP at week 12 than group I. Furthermore, group II had a lower incidence of severe radiographic abnormalities than group I at week 12. We confirmed previous observations that VLBW infants fed exclusively human milk require P and Ca supplementation to prevent metabolic bone disease of prematurity. |
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Authors:
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H Tsukahara; I Mitsuyoshi; T Sakaguchi; H Fukuhara; S Hayashi; K Nakamura |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta paediatrica Japonica; Overseas edition Volume: 31 ISSN: 0374-5600 ISO Abbreviation: Acta Paediatr Jpn Publication Date: 1989 Feb |
Date Detail:
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Created Date: 1989-09-15 Completed Date: 1989-09-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370357 Medline TA: Acta Paediatr Jpn Country: JAPAN |
Other Details:
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Languages: eng Pagination: 58-64 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bone and Bones
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metabolism* Humans Infant Food* Infant, Low Birth Weight* Infant, Newborn Milk, Human* Minerals / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Minerals |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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