Document Detail

Improved blood pressure control by monitoring compliance with antihypertensive therapy.
MedLine Citation:
PMID:  10344064     Owner:  NLM     Status:  MEDLINE    
Compliance with antihypertensive therapy was monitored for three months using an electronic medication dispenser in 35 patients remaining hypertensive despite the once-daily administration of a blood pressure lowering drug (either as monotherapy or as fixed-dose combination therapy). During the monitoring of compliance, the treatment was unchanged but blood pressure decreased significantly (p < 0.001) from 167.9/100.4 +/- 16.3/7.2 mmHg (mean +/- SD) to 152.5/90.9 +/- 20.9/11.5 mmHg. The percentage of days with one opening per day was 80.8 +/- 20.5. Thus, discussing with the patient about compliance with the prescribed drug regimen and monitoring compliance for a few months allows better control of blood pressure. This most likely reflects increased compliance with antihypertensive drug therapy.
B Waeber; W Vetter; R Darioli; U Keller; H R Brunner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of clinical practice     Volume:  53     ISSN:  1368-5031     ISO Abbreviation:  Int. J. Clin. Pract.     Publication Date:    1999 Jan-Feb
Date Detail:
Created Date:  1999-06-10     Completed Date:  1999-06-10     Revised Date:  2007-02-14    
Medline Journal Info:
Nlm Unique ID:  9712381     Medline TA:  Int J Clin Pract     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  37-8     Citation Subset:  IM    
Division of Hypertension and Vascular Medicine, CHUV, Lausanne, Switzerland.
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MeSH Terms
Aged, 80 and over
Antihypertensive Agents / therapeutic use*
Blood Pressure / drug effects*
Blood Pressure Monitors
Drug Delivery Systems / instrumentation*
Hypertension / drug therapy*
Middle Aged
Patient Compliance*
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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