| Improved aortic pulse wave velocity assessment from multislice two-directional in-plane velocity-encoded magnetic resonance imaging. | |
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MedLine Citation:
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PMID: 21031512 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the accuracy and reproducibility of aortic pulse wave velocity (PWV) assessment by in-plane velocity-encoded magnetic resonance imaging (MRI). MATERIALS AND METHODS: In 14 patients selected for cardiac catheterization on suspicion of coronary artery disease and 15 healthy volunteers, PWV was assessed with multislice two-directional in-plane velocity-encoded MRI (PWV(i.p.)) and compared with conventionally assessed PWV from multisite one-directional through-plane velocity-encoded MRI (PWV(t.p.)). In patients, PWV was also obtained from intraarterially acquired pressure-time curves (PWV(pressure)), which is considered the gold standard reference method. In volunteers, PWV(i.p.) and PWV(t.p.) were obtained in duplicate in the same examination to test reproducibility. RESULTS: In patients, PWV(i.p.) showed stronger correlation and similar variation with PWV(pressure) than PWV(t.p.) (Pearson correlation r = 0.75 vs. r = 0.58, and coefficient of variation [COV] = 10% vs. COV = 12%, respectively). In volunteers, repeated PWV(i.p.) assessment showed stronger correlation and less variation than repeated PWV(t.p.) (proximal aorta: r = 0.97 and COV = 10% vs. r = 0.69 and COV = 17%; distal aorta: r = 0.94 and COV = 12% vs. r = 0.90 and COV = 16%; total aorta: r = 0.97 and COV = 7% vs. r = 0.90 and COV = 13%). CONCLUSION: PWV(i.p.) is an improvement over conventional PWV(t.p.) by showing higher agreement as compared to the gold standard (PWV(pressure)) and higher reproducibility for repeated MRI assessment. |
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Authors:
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Jos J M Westenberg; Albert de Roos; Heynric B Grotenhuis; Paul Steendijk; Dennis Hendriksen; Pieter J van den Boogaard; Rob J van der Geest; Jeroen J Bax; J Wouter Jukema; Johan H C Reiber |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 32 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 1086-94 Citation Subset: IM |
Copyright Information:
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© 2010 Wiley-Liss, Inc. |
Affiliation:
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Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands. j.j.m.westenberg@lumc.nl |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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