Document Detail


Improved High-Fat Diet-Induced Glucose Intolerance by an Oral Administration of Phytosphingosine.
MedLine Citation:
PMID:  23291756     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We have previously reported that phytoceramide and phytosphingosine (PHS) stimulated the transcriptional activity of peroxisome proliferator-activated receptor γ (PPARγ) in cells. PPARγ is a therapeutic target for type 2 diabetes. We found in this study that an oral administration of PHS improved diet-induced glucose intolerance in mice. Since PHS is highly expressed in yeast, PHS in fermented foods may improve diabetes.
Authors:
Itsuo Murakami; Susumu Mitsutake; Naoyuki Kobayashi; Junko Matsuda; Akemi Suzuki; Tatsuro Shigyo; Yasuyuki Igarashi
Related Documents :
23512966 - Metabolic consequences of the early onset of obesity in common marmoset monkeys.
24170766 - Safety of nighttime 2-hour suspension of basal insulin in pump-treated type 1 diabetes ...
23062636 - Nucleotide-binding oligomerization domain-1 ligand induces inflammation and attenuates ...
23232606 - Wired on sugar: the role of the cns in the regulation of glucose homeostasis.
17980656 - Association between heart rate recovery and severity of obstructive sleep apnea syndrome.
21995866 - Hemichorea associated with non-ketotic hyperglycaemia: a case report.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-07
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  -     ISSN:  1347-6947     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Advanced Life Sciences, Hokkaido University.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Evaluation of Extraction Solutions for Biochemical Analyses of the Proteins in Rice Grains.
Next Document:  Role of Nitric Oxide-Detoxifying Enzymes in the Virulence of Pseudomonas aeruginosa against the Silk...