Document Detail

Improved Bloch-Siegert based B1 mapping by reducing off-resonance shift.
MedLine Citation:
PMID:  23355474     Owner:  NLM     Status:  MEDLINE    
An MRI method based on the Bloch-Siegert (BS) shift phenomenon was recently proposed as a fast and precise way to map a radio frequency (RF) transmit field (B1(+) field). For MRI at high field, the mapping sensitivity of this approach was limited by tissue heating associated with a BS irradiation pulse. To mitigate this, we investigated the possibility of lowering the off-resonance frequency of this pulse since theoretical analysis indicated that the sensitivity of Bloch-Siegert based B1(+) mapping could be substantially improved when irradiating closer to resonance. Using optimized irradiation pulse shape and gradient crushers to minimize direct excitation effects, in vivo experiments on human brains at 7 T confirmed improved sensitivity with this approach. Improved sensitivity translated into an 80% reduction in B1(+) estimation errors without increasing tissue heating. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
Qi Duan; Peter van Gelderen; Jeff Duyn
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural     Date:  2013-01-28
Journal Detail:
Title:  NMR in biomedicine     Volume:  26     ISSN:  1099-1492     ISO Abbreviation:  NMR Biomed     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-08-14     Completed Date:  2014-03-25     Revised Date:  2014-09-02    
Medline Journal Info:
Nlm Unique ID:  8915233     Medline TA:  NMR Biomed     Country:  England    
Other Details:
Languages:  eng     Pagination:  1070-8     Citation Subset:  IM    
Copyright Information:
Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
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MeSH Terms
Brain Mapping*
Computer Simulation
Magnetic Resonance Imaging / methods*
Grant Support

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