Document Detail

Imprint cytology improves accuracy of computed tomography-guided percutaneous transthoracic needle biopsy.
MedLine Citation:
PMID:  17928311     Owner:  NLM     Status:  MEDLINE    
The aim of the present study was to investigate whether imprint cytology can improve the diagnostic accuracy of computed tomography-guided transthoracic core biopsy. Between October 1997 and June 2004, thoracic lesions in 622 patients underwent biopsy using 19-gauge coaxial guiding needles and 20-gauge biopsy needles under computed tomography guidance. Touch imprint cytology and histopathology were performed for all biopsy specimens. Of these lesions, 431 (74.1%) were diagnosed as malignant, 151 (25.9%) as benign and 40 (6%) as nondiagnostic. Imprint cytology plus histology shows an improved diagnostic accuracy of 96.4% compared with that of imprint cytology alone (92.3%) or histopathology alone (93.0%). Procedure-related complications requiring further treatment occurred in eight (1.4%) patients. In conclusion, imprint cytology combined with histopathology can improve the diagnostic accuracy of computed tomography-guided transthoracic needle biopsy.
Y-C Chang; C-J Yu; W-J Lee; S-H Kuo; C-H Hsiao; I-S Jan; F-C Hu; H-M Liu; W-K Chan; P-C Yang
Publication Detail:
Type:  Journal Article     Date:  2007-10-10
Journal Detail:
Title:  The European respiratory journal     Volume:  31     ISSN:  1399-3003     ISO Abbreviation:  Eur. Respir. J.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-01     Completed Date:  2008-06-27     Revised Date:  2013-05-23    
Medline Journal Info:
Nlm Unique ID:  8803460     Medline TA:  Eur Respir J     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  54-61     Citation Subset:  IM    
Dept of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
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MeSH Terms
Aged, 80 and over
Biopsy, Needle
Cytological Techniques*
Lung Diseases / diagnosis*,  pathology
Middle Aged
Reproducibility of Results
Solitary Pulmonary Nodule / diagnosis*,  pathology
Tomography, X-Ray Computed / methods*

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