Document Detail

Impression cytology of the conjunctival epithelium in patients with vernal conjunctivitis.
MedLine Citation:
PMID:  8763308     Owner:  NLM     Status:  MEDLINE    
The alterations in the conjunctival epithelium during the course of vernal conjunctivitis were examined by conjunctival impression cytology. The study was carried out on 53 patients with vernal conjunctivitis and 20 normal subjects as control. The results of impression cytology demonstrated that all cytological parameters were significantly modified in vernal conjunctivitis patients; the earliest alterations were found in the distribution of goblet cells, in the intercellular junctions, in the chromatin morphology and in the degree of keratinisation. The morphometric comparison showed that in vernal conjunctivitis patients the mean number of goblet cells per field was significantly higher than in controls. Moreover the mean diameter of goblet cells was smaller in patients than in controls. Impression cytology can, therefore, be a simple, non-invasive and cheap method for the study of the ocular surface in vernal conjunctivitis.
P Aragona; G F Romeo; D Puzzolo; A Micali; G Ferreri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Eye (London, England)     Volume:  10 ( Pt 1)     ISSN:  0950-222X     ISO Abbreviation:  Eye (Lond)     Publication Date:  1996  
Date Detail:
Created Date:  1996-10-31     Completed Date:  1996-10-31     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  8703986     Medline TA:  Eye (Lond)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  82-5     Citation Subset:  IM    
Institute of Ophthalmology, Biomorphology, University of Messina, Italy.
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MeSH Terms
Child, Preschool
Conjunctiva / pathology*,  ultrastructure
Conjunctivitis, Allergic / pathology*
Cytological Techniques

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