Document Detail

Imported malaria in pregnancy: report of four cases and review of management.
MedLine Citation:
PMID:  1520785     Owner:  NLM     Status:  MEDLINE    
Malaria is a common infection worldwide. Increased travel by pregnant women makes it likely that physicians in the United States will see cases of malaria in this population. We observed four cases of malaria during pregnancy over an 8-month period at a general hospital in the United States. These cases illustrate the association between pregnancy and severe malaria in the mother and congenital infection in the newborn. We also noted delays in diagnosis because malaria was mistaken for other common illnesses. Therapy was complicated by concerns about the safety of antimalarial agents for the fetus and newborn as well as drug resistance. While chloroquine is safe for use in pregnancy, drug resistance is now common, especially when the etiologic organism is Plasmodium falciparum. There are concerns about the safety of administering other antimalarial agents during pregnancy (e.g., mefloquine). Concerns about the safety and availability of these agents limit options for prophylaxis.
D Subramanian; K J Moise; A C White
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  15     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-10-15     Completed Date:  1992-10-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  408-13     Citation Subset:  IM    
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030.
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MeSH Terms
Infant, Newborn
Malaria / congenital,  drug therapy,  parasitology*,  prevention & control
Malaria, Falciparum
Malaria, Vivax
Pregnancy Complications, Infectious / drug therapy,  parasitology*,  prevention & control
Comment In:
Clin Infect Dis. 1993 Oct;17(4):811-2   [PMID:  8268369 ]

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