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Importance of proper scaling of aerobic power when relating to cardiometabolic risk factors in children.
MedLine Citation:
PMID:  21749316     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: The relationship between cardiometabolic risk factors (CMRF) and aerobic power (VO(2max)) scaled as mL O(2) per kilogram body mass is controversial because mass includes both fat and fat-free mass, and fat mass is independently associated with the CMRF. Aim: To examine common units used to scale VO(2max) and their relationships to mean blood pressure (MBP), total cholesterol (TC), HDL cholesterol, triglycerides (TG), insulin resistance (HOMA-IR) and cumulative risk score (z-score). Subjects: 1784, 8?18 year-old youths, 938 girls and 886 boys. Methods: Fasting blood samples were obtained. VO(2max) was estimated in mL/min from cycle ergometry and scaled to body mass (kg), fat free mass (kg(FFM)), body surface area (m(2)), height (cm) and allometric (mL/kg(0.67)/min). Results: Unadjusted correlations between CMRF and many of the scaled VO(2max) units were significant (p?<?0.0001), especially for MBP, HOMA-IR, HDL and z-score, with lower correlations for TC and TG. After adjusting for ancestry, sex, height and body fat associations were greatly weakened (r?<?0.09), except for MBP. Conclusions: On a population basis, the physical characteristics of the child, especially body fat, are more related to CMRF than any scaled units of VO(2max); thus care is needed when relating fitness and health issues.
Authors:
Robert G McMurray; Peter A Hosick; Anna Bugge
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-13
Journal Detail:
Title:  Annals of human biology     Volume:  -     ISSN:  1464-5033     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404024     Medline TA:  Ann Hum Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Exercise and Sport Science, University of North Carolina , Chapel Hill, NC , USA.
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