Document Detail

Importance of early complex evaluation in high-risk pregnancy associated to diabetes mellitus. Case presentation and review of the literature.
MedLine Citation:
PMID:  22119836     Owner:  NLM     Status:  In-Data-Review    
We report and analyze a case of pregnancy associated with pre-existent diabetes mellitus and fetal congenital anomalies involving neural tube defect (NTD) and congenital heart defect (CHD). We discuss the early antenatal management of such high-risk pregnancies. The clinical course, maternal paraclinic profile and morpho-sonographic investigation of the fetus are described. A 28-year-old pregnant woman with pre-existing diabetes and a pre-pregnancy BMI 31 kg÷m², without preconception counseling for optimization of glycemic control was evaluated in our center for first trimester genetic screening at 12 weeks of gestation. Considering a high-risk pregnancy, careful fetal morphological assessment by ultrasound was performed; the extensive examination using high-resolution probes, both by transabdominal and transvaginal approach, found hypoplastic left heart syndrome (HLHS) and open spina bifida (OSB). Both anomalies present important difficulties regarding first trimester diagnostic. The couple was informed and chose termination of pregnancy (TOP). We consider that an anomaly scan at 12-13 + 6 gestational weeks by expert operators should be offered to high-risk pregnancies, because it provides the chance to detect the majority of fetal anomalies. This offer for couples the option of an early decision about the management of pregnancy in cases of severe fetal anomalies; postnatal treatment could be discussed as well as TOP and if the latter is chosen, the maternal risk and the potential psychological burden are lowered, as compared with TOP performed in the mid-second trimester.
Lavinia Gheorman; D Iliescu; Iuliana Ceauşu; Daniela Paulescu; I E Pleşea; V Gheorman
Related Documents :
3115446 - False positive results of tests for syphilis and outcome of pregnancy: a retrospective ...
2620716 - When urban adolescents choose abortion: effects on education, psychological status and ...
6644256 - Suction curettage.
15107166 - Social context and the experience of a sample of u.s. women taking ru-486 (mifepristone...
6714846 - Studies on ticks of veterinary importance in nigeria. viii. differences observed in the...
24327976 - Urinary nephrin: a new predictive marker for pregnancies with preeclampsia and small-fo...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie     Volume:  52     ISSN:  1220-0522     ISO Abbreviation:  Rom J Morphol Embryol     Publication Date:  2011  
Date Detail:
Created Date:  2011-11-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112454     Medline TA:  Rom J Morphol Embryol     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  1127-32     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova, Romania;
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Duodenal gastrointestinal stromal tumor.
Next Document:  Adjusting dento-alveolar morphology with orthodontic mini-implants (miniscrews). A clinical case rep...