Document Detail


Importance of circulating and urinary tissue kallikrein in the control of acute natriuresis and diuresis evoked by water immersion in man.
MedLine Citation:
PMID:  3544726     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In ten human subjects water immersion produced a two-fold diuresis and a three-fold increase in sodium secretion together with a marked fall in plasma renin activity and aldosterone. In contrast, circulating and urinary (active and total kallikrein) remained unchanged throughout the immersion period. Our results indicate that the acute diuresis and natriuresis evoked by water immersion in man is not regulated by circulating or urinary tissue kallikrein.
Authors:
P O'Hare; K Bhoola; I Chapman; J Roland; R Corrall
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  198 Pt B     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  1986  
Date Detail:
Created Date:  1987-03-16     Completed Date:  1987-03-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  225-32     Citation Subset:  IM; S    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aldosterone / blood
Diuresis*
Electrolytes / metabolism
Female
Humans
Immersion / physiopathology*
Kallikreins / blood*,  urine
Kidney / physiology,  physiopathology
Male
Middle Aged
Natriuresis*
Renin / blood
Sodium / metabolism
Chemical
Reg. No./Substance:
0/Electrolytes; 52-39-1/Aldosterone; 7440-23-5/Sodium; EC 3.4.21.-/Kallikreins; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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