Document Detail


Importance of the adrenergic nerve system in the response of gases in the arterial blood following the provoked bronchospasm.
MedLine Citation:
PMID:  23097963     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
INTRODUCTION: This work, partial pressure of the respiratory gases in the capillary blood (pH, PaO2, PaCO2) was studied, following the protective action of the beta2-drenergic stimulator-Hexoprenaline and alpha2-adrenergic blocker-Tolazoline in the bronchoconstriction caused by a beta-blocker-Propranolol.
MATERIAL AND METHODS: in patients with increased bronchial reactibility. pH, oxygen partial pressure (PaO2), dioxide carbon partial pressure (PaCO2) in the arterial blood, with the assistance of the analyzer IL, following some minutes of sample taking were defined in all patients. As a standard to verify the accuracy of the measurement, ampoule solutions of pH, PaO2 and PaCO2 were utilized (Acidobasel, Berlin).
RESULTS AND DISCUSSION: Following the inhalation of the beta-blocker-Propranolol (20 mg/ml-aerosol), there was an evident decrease (p < 0.05) of pO2 and a non-significant increase (p > 0.1) of pCO2. Beta2-adrenergcic stimulator-Hexoprenaline (2 inh x 0.2 mg), shows an protective effect in the decrease of pO2 (p < 0.05) following the bronchoconstriction being provoked by Propranolol. Alpha2-adrenergic blocker-Tolazoline (20 mg/ml-aerosol), has not shown a protective action in the bronchoconstriction caused with propranolol, therefore significant decrease (p < 0.05) of pO2 and a non-significant increase (p > 0.1) of pCO2 appeared. This shows that stimulation of beta2-adrenergic receptor has protective action in changes of the respiratory gases. Meantime, blocker of the alpha2-adrenergic receptor (Tolazoline) has not shown a protective action in changes of the respiratory gases.
Authors:
Hilmi Islami; Arta Veseli; Emir Behluli; Naim Morina
Related Documents :
18488253 - Growth monitoring of fibrobacter succinogenes by pressure measurement.
1054383 - Mandibular atrophy: a theory of its cause and prevention.
15117033 - Servo-controlled pneumatic pressure oscillator for respiratory impedance measurements a...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicinski arhiv     Volume:  66     ISSN:  0350-199X     ISO Abbreviation:  Med Arh     Publication Date:  2012  
Date Detail:
Created Date:  2012-10-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400722     Medline TA:  Med Arh     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  292-5     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, Faculty of Medicine, University of Prishtina. Clinical Centre, Prishtina, Kosova. islamihilmi@hotmail.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A case report of acute interstitial nephritis associated with antibiotic-impregnated orthopedic bone...
Next Document:  Mortality after acute myocardial infarction: significance of cardiovascular diabetic autonomic neuro...