Document Detail

The Importance of Dyspnoea in the diagnosis of Chronic Obstructive Pulmonary Disease - a descriptive analysis of a Stable Cohort in Portugal (SAFE Trial).
MedLine Citation:
PMID:  21549672     Owner:  NLM     Status:  Publisher    
INTRODUCTION: The aim of this study was to determine patient-perceived characteristics of Chronic Obstructive Pulmonary Disease (COPD) in patients participating in a large trial evaluating tiotropium bromide. PATIENTS AND METHODS: Baseline symptoms were assessed by means of a standardized questionnaire. Patients reported symptoms that led to diagnosis as well as their current most troublesome symptom. RESULTS: Data were obtained from 298 patients, mostly male (95%), with mean (standard deviation) baseline forced expiratory volume in 1 second of 1.1 (0.4) L (40.6 [13.3] % of predicted), mean disease duration of 14.4 (10.1) years and smoking history of 55.1 (25.3) pack-years. Dyspnoea was the most frequently reported symptom leading to COPD diagnosis (55.0% of patients), followed by cough (33.2%). Dyspnoea was also the current most troublesome symptom (82.6%), followed by cough (8.4%). The presence of dyspnoea or cough was independent of COPD severity. The most commonly reported co-morbidities were cardiovascular disorders (49% of patients), gastrointestinal disorders (20%) and metabolic disorders (16%), mainly diabetes mellitus. CONCLUSIONS: This analysis confirms the importance of dyspnoea as the most common symptom leading to initial COPD diagnosis and the symptom most troublesome to patients. Co-morbidities are common among COPD patients, and hence spirometric testing is appropriate in a patient who presents with dyspnoea associated with such a condition.
C Bárbara; J Moita; J Cardoso; R Costa; R Redondeiro; M Gaspar
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-13
Journal Detail:
Title:  Revista portuguesa de pneumologia     Volume:  -     ISSN:  0873-2159     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-5-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9813736     Medline TA:  Rev Port Pneumol     Country:  -    
Other Details:
Languages:  ENG; POR     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier España.
Serviço de Pneumologia II do Centro Hospitalar de Lisboa Norte, E.P.E. - Hospital Pulido Valente, Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Lisboa, Portugal.
Vernacular Title:
A Importância da Dispneia no diagnóstico da Doença Pulmonar Obstrutiva Crónica - uma análise descritiva de uma Coorte Estável em Portugal (Ensaio Clínico SAFE).
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