Document Detail


Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine.
MedLine Citation:
PMID:  16472342     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study is to report a possible implication of augmented vasogenic leakage in the mechanism of prolonged aura in sporadic hemiplegic migraine. A 35-year-old woman with sporadic hemiplegic migraine presented with headache followed by right arm weakness, right visual field defect, aphasia and confusion that persisted for 1 week. During the acute stage, focal hyperaemia was seen in the left cerebral hemisphere corresponding to persistent aura symptoms. Augmented vasogenic leakage was demonstrated on delayed enhanced fluid-attenuated inversion recovery image. Magnetic resonance angiography showed dilation of the left middle cerebral artery. During the convalescent stage, such abnormal findings were not seen. Based on these results, we speculate that augmented vasogenic leakage from the leptomeningeal vessels, probably associated with activation of the trigeminovascular system, may delay the recovery of hemiplegic migraine aura.
Authors:
T Iizuka; F Sakai; K Suzuki; H Igarashi; N Suzuki
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cephalalgia : an international journal of headache     Volume:  26     ISSN:  0333-1024     ISO Abbreviation:  Cephalalgia     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-13     Completed Date:  2006-05-16     Revised Date:  2008-02-11    
Medline Journal Info:
Nlm Unique ID:  8200710     Medline TA:  Cephalalgia     Country:  England    
Other Details:
Languages:  eng     Pagination:  332-5     Citation Subset:  IM    
Affiliation:
Department of Neurology, School of Medicine, Kitasato University, Kanagawa, Japan. takahiro@med.kitasato-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex Hormones / therapeutic use
Adult
Brain Edema / complications*,  drug therapy
Female
Hemiplegia / etiology
Humans
Magnetic Resonance Angiography
Migraine with Aura / physiopathology*
Vision Disorders / drug therapy,  etiology*,  physiopathology
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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