Document Detail


Implementation of flow cytometry in the diagnostic work-up of myelodysplastic syndromes in a multicenter approach: Report from the Dutch Working Party on Flow Cytometry in MDS.
MedLine Citation:
PMID:  21982641     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Flow cytometry (FC) is recognized as an important tool in the diagnosis of myelodysplastic syndromes (MDS) especially when standard criteria fail. A working group within the Dutch Society of Cytometry aimed to implement FC in the diagnostic work-up of MDS. Hereto, guidelines for data acquisition, analysis and interpretation were formulated. Based on discussions on analyses of list mode data files and fresh MDS bone marrow samples and recent literature, the guidelines were modified. Over the years (2005-2011), the concordance between the participating centers increased indicating that the proposed guidelines contributed to a more objective, standardized FC analysis, thereby ratifying the implementation of FC in MDS.
Authors:
Theresia M Westers; Vincent H J van der Velden; Canan Alhan; Roelof Bekkema; André Bijkerk; Rik A Brooimans; Claudia Cali; Angelika M Dräger; Valerie de Haas; Christa Homburg; Anja de Jong; P Ellen A Kuiper-Kramer; Marije Leenders; Ingrid Lommerse; Jeroen G Te Marvelde; Joke K van der Molen-Sinke; Bijan Moshaver; Andre B Mulder; Frank W M B Preijers; Roger K Schindhelm; Alita van der Sluijs; Elisabeth R van Wering; August H Westra; Arjan A van de Loosdrecht;
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-5
Journal Detail:
Title:  Leukemia research     Volume:  -     ISSN:  1873-5835     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7706787     Medline TA:  Leuk Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands.
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