Document Detail


Implantation strategy of the atrial dipole impacts atrial sensing performance of single lead VDD pacemakers.
MedLine Citation:
PMID:  11990661     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intermittent atrial undersensing is observed in a considerable percentage of patients with single lead VDD pacemakers. Analyzing the 2-year data of the Saphir Multicenter Follow-Up Study, the authors investigated predictors for the occurrence of undersensing. The study included 194 patients with high degree AV block who received a VDD pacemaker system with an identical sensing amplifier. Placement strategy of the atrial dipole was left to the discretion of the implanting physician. At the final position, atrial potential amplitudes were measured during deep and shallow respiration. Atrial dipole position was determined by intraoperativefluoroscopy subdividing the right atrium in a high, mid, and low portion. Undersensing was defined by evidence of at least one not sensed P wave during Holter monitoring or exercise testing and by the presence of 0.1-0.2 mV amplitudes in the P wave amplitude histogram of the pacemaker. Incidence of undersensing was 25.8%; 9.3% of patients showed frequent (> 5%) or symptomatic undersensing. Patients with undersensing were older (76.6 +/- 10.6 vs 64.2 +/- 14.8 years), showed a lower minimum of intraoperative atrial potential amplitude (P(min) 0.86 +/- 0.64 vs 1.43 +/- 0.77 mV), a wider range of potential amplitude (deltaP 1.71 +/- 1.44 vs 0.94 +/- 0.84 mV), and a higher incidence of dipole placement in the low right atrium (50.0% vs 11.1 %, P < 0.001 for all comparisons). In a multivariate regression analysis, patient age > 66 years, Pmin < 0.6 mV, > 1.3 mV and atrial dipol placement in the lowright atrium were independently predictive for undersensing. Minimal atrialpotential amplitude, range of potential amplitude, and atrial dipole position influence atrial sensing performance in single lead VDD pacing. Thus, implantation guidelines should reflect these rules to improve the outcome of VDD pacemaker recipients.
Authors:
Uwe K H Wiegand; Bernd Nowak; Udo Reisp; Torsten Peiffer; Frank Bode; Jürgen Potratz;
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  25     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-05-06     Completed Date:  2002-12-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  316-23     Citation Subset:  IM    
Affiliation:
Medical University of Luebeck, Department of Internal Medicine II, Germany. uwe.wiegand;vamedinf.mu-luebeck.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Atrioventricular Node / physiopathology*
Cardiac Pacing, Artificial*
Electrocardiography
Equipment Design
Equipment Failure
Female
Follow-Up Studies
Heart Atria / physiopathology
Heart Block / physiopathology,  therapy*
Humans
Male
Middle Aged
Multicenter Studies as Topic
Retrospective Studies
Sensitivity and Specificity
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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