| Impedance planimetric description of normal rectoanal motility in humans. | |
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MedLine Citation:
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PMID: 17762962 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Manometry and pressure-volume measurements are commonly used to study anorectal physiology. However, the methods are limited by several sources of error. Recently, a new impedance planimetric system has been introduced in a porcine model. It allows simultaneous determination of anorectal pressures and multiple rectal luminal cross-sectional areas. This study was designed to study normal human rectoanal motility by means of impedance planimetry with multiple rectal cross-sectional areas and rectal and anal pressure. METHODS: Twelve healthy volunteers (10 females), aged 24 to 53 years, were studied during one-hour fasting and one hour after a meal. Rectal cross-sectional areas were determined at five levels each 2 cm apart, as well as rectal and anal pressure. RESULTS: A number of rectoanal motility patterns were observed. A total of 25 episodes with very localized cyclic rectal contractions detected at only one of five channels were observed lasting two to four minutes with a median frequency of three per minute (range, 2-6). A total of 44 episodes of cyclic rectal contractions propagating over two or more channels were detected lasting 2 to 36 minutes. Most were associated with contractions of the anal canal. A significant increase in rectal contractile activity was observed after the meal (P < 0.05). Single rectal contractions were observed in 11 subjects, and the majority were located to one channel and lasted less than 40 seconds. In two subjects who felt a need to defecate during the experiment, the cross-sectional area at all channels showed strong cyclic contractile activity and the anal pressure increased by approximately 100 percent. CONCLUSIONS: The new rectal impedance planimetry system allows highly detailed description of rectoanal motility patterns. It has promise as a new method for description of rectoanal motility in further studies. |
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Authors:
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Inge S Andersen; Hanne B Michelsen; Klaus Krogh; Steen Buntzen; Søren Laurberg |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Diseases of the colon and rectum Volume: 50 ISSN: 0012-3706 ISO Abbreviation: Dis. Colon Rectum Publication Date: 2007 Nov |
Date Detail:
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Created Date: 2007-11-08 Completed Date: 2008-01-29 Revised Date: 2008-10-21 |
Medline Journal Info:
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Nlm Unique ID: 0372764 Medline TA: Dis Colon Rectum Country: United States |
Other Details:
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Languages: eng Pagination: 1840-8 Citation Subset: IM |
Affiliation:
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Institute for Experimental Clinical Research, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anal Canal / physiology Defecation / physiology* Female Gastrointestinal Motility / physiology* Humans Male Middle Aged Muscle Contraction / physiology Muscle, Smooth / physiology Postprandial Period / physiology Pressure Rectum / physiology* |
| Comments/Corrections | |
Comment In:
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Dis Colon Rectum. 2008 Oct;51(10):1584-5; author reply 1586
[PMID:
18670813
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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