| Impedance-pH Monitoring and Conventional pH Monitoring Are Complementary Methods to Detect Association between Gastroesophageal Reflux and Apnea-related Symptoms in Preterm Infants and Neonates. | |
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MedLine Citation:
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PMID: 22694343 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Objective: To investigate the usefulness of Multichannel intraluminal impedance-pH (MII-pH) monitoring as compared with conventional pH monitoring for detecting Gastroesophageal reflux (GER) episodes and apnea-related symptom association in preterm infants and neonates. Methods: Twenty-three infants (16 preterm and 7 term infants) in hospital, who underwent 24-hour MII-pH monitoring, were studied retrospectively. GER indices and apnea-related symptom association were measured by both MII-pH and conventional pH based analysis. Results: Of the total 998 GER episodes assessed by MII-pH monitoring, 407 (40.8%) were acidic and 590 (59.1%) were weakly acidic. A total of 1,689 GER episodes were detected by conventional pH based analysis and 270 (16%) were related to retrograde bolus movement. A total of 313 apnea-related symptoms were reported. Five patients had a positive symptom association: 3 by MII-pH, 1 by both MII-pH and conventional pH, 1only by conventional pH. Conclusions: Addition of MII-pH monitoring to conventional pH monitoring improves the diagnostic yield of symptom association analysis in preterm infants and neonates with apnea-related symptoms. Conventional pH monitoring is still important in the era of impedance measurement. |
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Authors:
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Myung Seok Shin; Jeong Ok Shim; Jin Soo Moon; Han Suk Kim; Jae Sung Ko; Jung-Hwan Choi; Jeong Kee Seo |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-14 |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: - ISSN: 1476-4954 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-6-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Pediatrics Seoul National University College of Medicine. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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