| Impedance cardiography in the diagnosis of capillary leak syndrome caused by doxorubicin therapy in a patient with myeloma multiplex. | |
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MedLine Citation:
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PMID: 20104463 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cytotoxicity of drugs can be a cause of cardiorespiratory disorders connected with chemotherapy. Doxorubicin is an antibiotic from the group of anthracyclines effective in antineoplastic therapy of solid and hematopoetic tumors. The most common cause of therapy ceasing is its cardiotoxicity. However, a lung injury connected with its cytotoxic activity to pulmonary endothelium (capillary leak syndrome) can be an equally serious complication. In the case presented, rapid, multi-profile diagnostics with the use of impedance cardiography, a modern noninvasive tool of hemodynamic monitoring, led to the recognition and effective treatment of a rare clinical syndrome. |
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Authors:
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Pawe? Krzesi?ski; Robert Wierzbowski; Grzegorz Gielerak; Janusz Ha?ka; Oxana Matysiak; Pawe? Smurzy?ski |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Cardiology journal Volume: 17 ISSN: 1897-5593 ISO Abbreviation: Cardiol J Publication Date: 2010 |
Date Detail:
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Created Date: 2010-01-27 Completed Date: 2010-04-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101392712 Medline TA: Cardiol J Country: Poland |
Other Details:
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Languages: eng Pagination: 88-91 Citation Subset: IM |
Affiliation:
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Department of Cardiology and Internal Diseases, Military Institute of the Health Services, Warszawa, Poland. pakrzesinski@interia.pl |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antibiotics, Antineoplastic / adverse effects* Antineoplastic Combined Chemotherapy Protocols / therapeutic use Capillary Leak Syndrome / chemically induced*, diagnosis* Cardiography, Impedance* Cyclophosphamide / therapeutic use Doxorubicin / adverse effects* Humans Lung / blood supply* Male Melphalan / therapeutic use Multiple Myeloma / drug therapy* Prednisone / therapeutic use Retreatment Treatment Outcome Vincristine / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Antibiotics, Antineoplastic; 0/VMCP protocol; 148-82-3/Melphalan; 23214-92-8/Doxorubicin; 50-18-0/Cyclophosphamide; 53-03-2/Prednisone; 57-22-7/Vincristine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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