Document Detail


Impedance of Novel Therapeutic Technologies: The Case of Stem Cells.
MedLine Citation:
PMID:  23067356     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Embryonic stem cell (ES) technology has advanced considerably within the past three decades and has gained prominent distinction within the emerging field of regenerative medicine. As it now enters the nascent stages of clinical application, many hopes and expectations arise along with questions as to where the technology will go. This paper evaluates the technical and practical obstacles that must be overcome before it can fully translate into the clinical context, the existence of strong opposition to the technology, political and legal barriers that have impeded its progression, and the role of healthcare reform in creating new social and economic priorities. In contrast to the technological imperative, a driving force seeking to implement the most recent scientific advances into medical practice, we refer to such translational obstacles as "technological impedance." Rather than expending inordinate effort to preserve existing systems that continue to possess major hurdles, we advocate fostering interdisciplinary approaches in the development of new generation platforms and embracing disruptive innovations that create solutions to technological impedance and move us forward in healthcare delivery. Clin Trans Sci 2012; Volume 5: 422-427.
Authors:
David G Zacharias; Timothy J Nelson; Paul S Mueller; C Christopher Hook
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-28
Journal Detail:
Title:  Clinical and translational science     Volume:  5     ISSN:  1752-8062     ISO Abbreviation:  Clin Transl Sci     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474067     Medline TA:  Clin Transl Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  422-427     Citation Subset:  -    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Affiliation:
Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA Mayo Medical School, Mayo Clinic College of Medicine, Rochester, Minnesota, USA Division of General Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA Division of Hematology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota, USA Program in Professionalism and Ethics, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
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