| Impairments of action control in the context of neuropsychological findings in schizophrenia | |
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MedLine Citation:
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PMID: 17380466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Based on a review of neurobiological and neuropsychological findings in schizophrenia, we illustrate how experimental neuropsychological research contributes to the understanding of schizophrenia. It is shown that cognitive performance deficits are a central feature of schizophrenia. They are closely connected with changes of brain physiology and appear to reflect disturbances of basic cognitive functions. It is difficult to identify these functions, because task performance usually taps various cognitive processes. However, isolation of functions is possible by experimental variation of tasks that require a small number of well defined processes. To illustrate this, we review several recent studies that experimentally analyzed deficits in the control of fast eye movements (saccades). In the antisaccade task schizophrenia patients show distinct, temporally stable and often replicated performance deficits. The reviewed studies suggest that these deficits predominantly reflect a weakness in the volitional initiation of action. |
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Authors:
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B Reuter; N Kathmann |
Publication Detail:
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Type: English Abstract; Journal Article; Review Date: 2007-03-23 |
Journal Detail:
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Title: Fortschritte der Neurologie-Psychiatrie Volume: 75 ISSN: 0720-4299 ISO Abbreviation: Fortschr Neurol Psychiatr Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-10-04 Completed Date: 2007-12-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8103137 Medline TA: Fortschr Neurol Psychiatr Country: Germany |
Other Details:
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Languages: ger Pagination: 607-16 Citation Subset: IM |
Affiliation:
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Humboldt-Universität zu Berlin, Institut für Psychologie, Berlin. reuter@psychologie.hu-berlin.de |
Vernacular Title:
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Störungen der Handlungskontrolle im Kontext neuropsychologischer Befunde bei Schizophrenie. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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pathology,
physiopathology Cognition / physiology Humans Psychomotor Performance / physiology Saccades / physiology Schizophrenia / pathology, physiopathology* Schizophrenic Psychology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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