Document Detail


Impairment of thermogenesis and heat conservation in rats during 3 hours of 3-G exposure.
MedLine Citation:
PMID:  6466250     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Heat conservation and production were studied in rats at 3 G and at 1 G. A closed-circuit system that includes a Krogh-type spirometer for the continuous measurement of oxygen consumption was used to determine heat production. At the same time, core temperature (Tc) and tail temperature (Tt) were also measured. During the first 20 min at 3 G, oxygen consumption increased by at most 18% in some of the rats and fell by up to 15% in the remaining rats. However, in all rats at 3 G, there was a fall of Tc during this time. Thus, the initial fall of Tc at 3 G was independent of concurrent changes in the rate of oxygen consumption. Furthermore, the rapid fall in Tc during the initial exposure to hypergravity was not due to reduced heat production (since oxygen consumption was variable and in some rats increased) but to an increase in heat loss. Even after 3 h at 3 G, when heat conservation mechanisms had recovered, the rate of oxygen consumption in rats was not significantly increased relative to the 1 G rate; hence thermogenesis was not activated to rewarm the animal.
Authors:
C B Monson; J M Horowitz
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Aviation, space, and environmental medicine     Volume:  55     ISSN:  0095-6562     ISO Abbreviation:  Aviat Space Environ Med     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-09-11     Completed Date:  1984-09-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501714     Medline TA:  Aviat Space Environ Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  542-5     Citation Subset:  IM; S    
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MeSH Terms
Descriptor/Qualifier:
Animals
Body Temperature Regulation*
Gravitation*
Male
Oxygen Consumption
Rats
Restraint, Physical
Skin Temperature
Tail / blood supply

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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