Document Detail


Impairment of some granulocyte functions in Sweet's syndrome.
MedLine Citation:
PMID:  1350393     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chemotaxis, phagocytic and intracellular killing activities of polymorphonuclear leukocytes (PMNL) were investigated in vitro in 7 patients suffering from the acute phase of Sweet's syndrome. A moderate but consistent impairment of neutrophilic chemotactic activity (NCA) was revealed in all patients. Intracellular killing of blastospores of Candida albicans was diminished in 5/7 patients. Phagocytosis and oxidase activities were within normal levels. These results point to an alteration of some PMNL functions in the acute phase of Sweet's syndrome.
Authors:
P von den Driesch; M Simon; R Schlegel Gomez; O P Hornstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  72     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1992  
Date Detail:
Created Date:  1992-06-24     Completed Date:  1992-06-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  109-11     Citation Subset:  IM    
Affiliation:
Department of Dermatology, University of Erlangen-Nürnberg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Candida albicans
Chemotaxis, Leukocyte
Cytotoxicity, Immunologic
Female
Humans
Male
Middle Aged
Neutrophils / physiology*
Phagocytosis
Sweet Syndrome / immunology,  physiopathology*

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