| Impaired vascular responses to nitroglycerin in subjects with coronary atherosclerosis. | |
| | |
MedLine Citation:
|
PMID: 11152844 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To study smooth muscle function in atherosclerosis, we calculated dose-response curves in patients with coronary artery disease and in controls by measuring changes in brachial artery diameter after incremental sublingual doses of nitroglycerin. The doses required to produce a 50% maximal dilator response were significantly higher in patients with coronary artery disease than in controls (p <0.002), suggesting smooth muscle dysfunction in atherosclerosis. |
| | |
Authors:
|
O T Raitakari; J P Seale; D S Celermajer |
Related Documents
:
|
6444354 - Relationship of small and large coronary artery disease to myocardial ischemia. 15240574 - Clinical review 168: what vascular ultrasound testing has revealed about pediatric athe... 9665974 - Kawasaki syndrome. 8368064 - Risk factors of coronary arterial aneurysm in kawasaki disease. 6503254 - Transventricular simple-capacitor discharge defibrillation thresholds after coronary li... 22794334 - Opportunities in abdominal aortic aneurysm research: epidemiology, genetics, and pathop... |
Publication Detail:
|
Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The American journal of cardiology Volume: 87 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2001 Jan |
Date Detail:
|
Created Date: 2001-02-01 Completed Date: 2001-02-08 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 217-9, A8 Citation Subset: AIM; IM |
Affiliation:
|
Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Brachial Artery / drug effects, ultrasonography Coronary Artery Disease / drug therapy* Dose-Response Relationship, Drug Humans Linear Models Male Middle Aged Muscle, Smooth, Vascular / drug effects* Nitroglycerin / pharmacology* Vasodilator Agents / pharmacology* |
| Chemical | |
Reg. No./Substance:
|
0/Vasodilator Agents; 55-63-0/Nitroglycerin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prognostic value of peak exercise systolic blood pressure on long-term survival after myocardial inf...
Next Document: Instability of coronary lesions in unstable angina assessed by C-reactive protein values following c...