Document Detail

Impaired transduction of R213 and its recovery by a homologous resident R factor.
MedLine Citation:
PMID:  4929864     Owner:  NLM     Status:  MEDLINE    
Transduction by Plkc of drug-resistance markers of the factor R213 was shown to occur at an exceptionally low frequency (at less than 10(-8) of the input phage), and they could not be transduced by P22. When the recipient cells carried a homologous R factor derived from R213, markers were transduced by Plkc at a normal frequency (at about 10(-5) to 10(-6) of the input phage). Derivative R factors, transducible by Plkc at a normal frequency but being transferred by conjugation at a frequency lower than that of the original R213, were obtained. This type of transductant often segregated R(-) cells. In addition, several transductants contained R factors which were transferred normally by conjugation but were transduced by Plkc at as low a frequency as the original R213. This type of transductant was an effective recipient for transduction by Plkc of R213 when apparently "cured" by acridine treatment. No such effective "cured" recipients were obtained from the transductants with derivatives of R213 transducible at a normal frequency. Two possible interpretations are presented: (i) R213 produces a bacteriocin-like substance upon transduction, or (ii) the genome size of R213 is too large for all of its determinants to be transduced.
M Yoshikawa; Y Hirota
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bacteriology     Volume:  106     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1971 May 
Date Detail:
Created Date:  1971-06-26     Completed Date:  1971-06-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  523-8     Citation Subset:  IM    
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MeSH Terms
Acridines / pharmacology
Conjugation, Genetic
Culture Media
Drug Resistance, Microbial*
Models, Theoretical
Salmonella Phages*
Salmonella typhimurium / drug effects*,  radiation effects
Shigella / drug effects*,  radiation effects
Transduction, Genetic*
Ultraviolet Rays
Reg. No./Substance:
0/Acridines; 0/Culture Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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