Document Detail


Impaired transduction of R213 and its recovery by a homologous resident R factor.
MedLine Citation:
PMID:  4929864     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transduction by Plkc of drug-resistance markers of the factor R213 was shown to occur at an exceptionally low frequency (at less than 10(-8) of the input phage), and they could not be transduced by P22. When the recipient cells carried a homologous R factor derived from R213, markers were transduced by Plkc at a normal frequency (at about 10(-5) to 10(-6) of the input phage). Derivative R factors, transducible by Plkc at a normal frequency but being transferred by conjugation at a frequency lower than that of the original R213, were obtained. This type of transductant often segregated R(-) cells. In addition, several transductants contained R factors which were transferred normally by conjugation but were transduced by Plkc at as low a frequency as the original R213. This type of transductant was an effective recipient for transduction by Plkc of R213 when apparently "cured" by acridine treatment. No such effective "cured" recipients were obtained from the transductants with derivatives of R213 transducible at a normal frequency. Two possible interpretations are presented: (i) R213 produces a bacteriocin-like substance upon transduction, or (ii) the genome size of R213 is too large for all of its determinants to be transduced.
Authors:
M Yoshikawa; Y Hirota
Related Documents :
1377704 - Basal and regulated secretion of insulin-like growth factor binding proteins in osteobl...
22314264 - Effects of lobaplatin as a single agent and in combination with trail on the growth of ...
1966284 - Effect of suramin on growth of androgen-responsive mouse tumor (shionogi carcinoma 115)...
6156454 - Insulin-treated 3t3-l1 adipocytes and cell-free extracts derived from them incorporate ...
8735884 - Cancer and malignant resistance of cells as phenomena of adaptation to damaging factors.
20885774 - A mathematical model of β-cells in an islet of langerhans sensing a glucose gradient.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bacteriology     Volume:  106     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1971 May 
Date Detail:
Created Date:  1971-06-26     Completed Date:  1971-06-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  523-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acridines / pharmacology
Adsorption
Bacteriophages*
Conjugation, Genetic
Culture Media
Drug Resistance, Microbial*
Models, Theoretical
Mutation
Salmonella Phages*
Salmonella typhimurium / drug effects*,  radiation effects
Shigella / drug effects*,  radiation effects
Transduction, Genetic*
Ultraviolet Rays
Chemical
Reg. No./Substance:
0/Acridines; 0/Culture Media
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Interaction between the first enzyme for histidine biosynthesis and histidyl transfer ribonucleic ac...
Next Document:  Beginning a genetic analysis of conjugational transfer determined by the F factor in Escherichia col...