Document Detail

Impaired left ventricular diastolic function in acromegaly: an echocardiographic study.
MedLine Citation:
PMID:  3494364     Owner:  NLM     Status:  MEDLINE    
To study diastolic function we digitized M-mode echocardiograms in 18 acromegalic patients (A) and compared them to an age matched control population (C). Wall thickness and left ventricular (LV) mass index are frankly increased in A (p less than 0.001). Filling pattern of the LV shows in A a prolongation of the isovolumic relaxation period (IRP) (p less than 0.001), an increase of the percentage dimension change of LV during IRP (p less than 0.001) and a reduction of the percentage dimension change during the rapid filling period (p less than 0.01). Our results indicate that relaxation is abnormal in A; this abnormality should be interpreted as a mere consequence of LV hypertrophy.
P D Bertoni; G Morandi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cardiologica     Volume:  42     ISSN:  0001-5385     ISO Abbreviation:  Acta Cardiol     Publication Date:  1987  
Date Detail:
Created Date:  1987-05-11     Completed Date:  1987-05-11     Revised Date:  2009-06-11    
Medline Journal Info:
Nlm Unique ID:  0370570     Medline TA:  Acta Cardiol     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  1-10     Citation Subset:  IM    
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MeSH Terms
Acromegaly / physiopathology*
Heart / physiopathology*
Heart Ventricles / physiopathology
Middle Aged
Myocardial Contraction*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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