| Impaired left ventricular diastolic filling occurs in diabetic patients without atherosclerotic coronary artery disease. | |
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MedLine Citation:
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PMID: 9075428 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using left ventriculography, left ventricular diastolic function was studied in 24 diabetic patients who had angina pectoris without atherosclerotic large-vessel coronary artery diseases (group A, 14 patients with exercise-induced ischemic ST-T changes as seen during electrocardiogram; group B, 10 patients without such changes). In groups A and B, the global peak filling rate was significantly less than that in control patients without diabetes or cardiac diseases. The ratio of the global time to the peak filling rate to the diastolic time was higher in both groups A and B than in the control groups. However, the total of time differences, defined as the sum of the time differences between global time to the peak filling rate and each of the three regional time to the peak filling rate, was greater in group A than in either group B or the control patients. Total time difference was similar in group B and the controls. Left ventricular diastolic filling was impaired in diabetic patients without large-vessel coronary artery disease. Impaired diastolic filling was present regionally in patients with ischemic ST-T change but globally in those without such change. |
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Authors:
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T Inoue; T Fujito; S Asahi; K Hoshi; Y Sakai; S Morooka |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of the medical sciences Volume: 313 ISSN: 0002-9629 ISO Abbreviation: Am. J. Med. Sci. Publication Date: 1997 Mar |
Date Detail:
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Created Date: 1997-04-10 Completed Date: 1997-04-10 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370506 Medline TA: Am J Med Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 125-30 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, Koshigaya Hospital, Dokkyo University School of Medicine, Saitama, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Coronary Artery Disease / physiopathology* Coronary Circulation Diabetes Mellitus / physiopathology* Diastole* Female Humans Male Microcirculation / physiopathology Middle Aged Ventricular Dysfunction, Left / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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