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Impaired global and segmental myocardial deformation assessed by 2-dimensional speckle tracking echocardiography in patients with vitamin B12 deficiency.
MedLine Citation:
PMID:  23799551     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Contrary effects of vitamin B12 deficiency have been shown on the cardiovascular system. Aim of our study was to analyze left ventricular (LV) myocardial deformation, by use of two dimensional (2D) speckle tracking echocardiography (STE) in patients with vitamin B12 deficiency and normal LV ejection fraction. : METHODS: Twenty-five patients with vitamin B12 deficiency (B12 levels < 200 pg/ml; mean age: 29.6 ± 8.2 y, 15 female), and 27 healthy controls (B12 levels > 200 pg/ml; mean age: 30.1 ± 6.9 y, 13 female) were included in the study. 2D echocardiography images were transferred to a workstation for further offline analysis. Longitudinal peak systolic (LPSS) and global strain (LGS) was obtained from four chamber and apical long axis (APLAX) views. : RESULTS: Standard echocardiographic parameters and tissue Doppler imaging (TDI) velocities were comparable between groups. All LPSS values in the patient group except for apical 4C septal wall longitudinal strain were significantly decreased than those in the control group. There was a positive correlation between B12 levels and strain values except apical 4C septal wall strain values.
CONCLUSIONS: We found that in patients with B12 deficiency, global and segmental myocardial deformation : was impaired and this impairment was correlated with the levels of vitamin B12.
Authors:
Zekeriya Kaya; Asuman Bicer; Funda Yalcin; Arzu Er; Aysun Camuzcuoğlu; Nurhan Korkmaz; Yusuf Sezen
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-6-25
Journal Detail:
Title:  Cardiology journal     Volume:  -     ISSN:  1897-5593     ISO Abbreviation:  Cardiol J     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-6-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101392712     Medline TA:  Cardiol J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Harran University. asubicer@yahoo.com.
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