| Impaired continuity of flow in congenital heart disease with single ventricle physiology. | |
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MedLine Citation:
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PMID: 20972206 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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We report the comprehensive evaluation of cardiac morphology, valve function, and three-dimensional (3D) blood flow in a pediatric patient with congenital heart disease. 3D visualization of cardiovascular flow paths and quantitative flow analysis based on flow-sensitive 4D magnetic resonance imaging (MRI) provided detailed insight into hemodynamic changes associated with valve insufficiency and the complex single ventricle physiology. Despite only moderate atrio-ventricular regurgitation (fraction=28%) a marked redirection of atrial flow and pronounced vortex flow in the entire atrium was observed. Disturbed retrograde flow was even found upstream within the left pulmonary veins (regurgitant fraction=27%) indicating interrupted continuity of flow directed through the single atrium and ventricle. Such findings indicate the potential of flow-sensitive 4D MRI to detect and quantify complex 3D flow alterations. |
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Authors:
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Michael Markl; Julia Geiger; Brigitte Stiller; Raoul Arnold |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-10-23 |
Journal Detail:
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Title: Interactive cardiovascular and thoracic surgery Volume: 12 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
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Languages: eng Pagination: 87-90 Citation Subset: IM |
Affiliation:
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Department of Radiology, Medical Physics, University Hospital Freiburg, Breisacher Str. 60a, 79106 Freiburg, Germany. michael.markl@uniklinik-freiburg.de |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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