| Impaired avidity maturation after tetanus toxoid booster in children with down syndrome. | |
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MedLine Citation:
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PMID: 21057373 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Down syndrome children show a decreased avidity of the antibody response after tetanus toxoid booster vaccination at 9 years of age suggesting impaired memory B cell selection in the germinal center. Clinicians need to be aware of this ongoing subtle immunologic deficit in Down syndrome. |
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Authors:
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Maaike A Kusters; C M Jol-van der Zijde; Maarten J van Tol; W E Bolz; L A Bok; Marjan Visser; Esther de Vries |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Pediatric infectious disease journal Volume: 30 ISSN: 1532-0987 ISO Abbreviation: Pediatr. Infect. Dis. J. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8701858 Medline TA: Pediatr Infect Dis J Country: United States |
Other Details:
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Languages: eng Pagination: 357-9 Citation Subset: IM |
Affiliation:
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From the *Department of Pediatrics, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands; †Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands; ‡Department of Pediatrics, Elkerliek Hospital, Helmond, The Netherlands; §Department of Pediatrics, Máxima Medical Center, Veldhoven, The Netherlands; and ¶Department of Pediatrics, Beatrix Hospital, Gorinchem, The Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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