Document Detail


Impaction bone grafting with freeze-dried irradiated bone. Part II. Changes in stiffness and compactness of morselized grafts: experiments in cadavers.
MedLine Citation:
PMID:  14620975     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the technique of impaction bone grafting, implant stability depends on the mechanical properties of the impacted morselized grafts. Although the procedure is usually performed with fresh-frozen femoral heads, there is still some concern about their supply and safety. Bone processing is a potential solution, but the mechanical properties of this material during and after impaction need to be determined. We used 6 osteoarthrotic femoral heads to prepare two paired batches of morselized bone. One batch was morselized and frozen. The other batch was chemically treated, morselized, freeze-dried and then gamma-irradiated. We impacted 18 samples from each batch in a contained cylinder. Freeze-dried bone grafts were tested after 30 minutes of rehydration. The changes in the compactness and stiffness of the material were monitored during the impaction. The compaction of the freeze-dried bone was faster than that of their fresh-frozen control. The maximal stiffness reached by both materials was the same (55 MPa), but the freeze-dried grafts required three to four times fewer impactions to achieve that stiffness. After 3, 10 and 50 impactions the freeze-dried bone was stiffer than the fresh-frozen bone. As it is easier to impact, the freeze-dried bone may be mechanically more efficient than the fresh-frozen bone in surgical conditions. Moreover, the processed bone meets the highest safety standards, as regards the risk of disease transmission.
Authors:
Olivier Cornu; Ashit Bavadekar; Bernard Godts; John Van Tomme; Christian Delloye; Xavier Banse
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta orthopaedica Scandinavica     Volume:  74     ISSN:  0001-6470     ISO Abbreviation:  Acta Orthop Scand     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-11-17     Completed Date:  2003-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370352     Medline TA:  Acta Orthop Scand     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  553-8     Citation Subset:  IM    
Affiliation:
Orthopaedic Research Laboratory, Université Catholique de Louvain, Brussels, Belgium. cornu@orto.ucl.ac.be
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MeSH Terms
Descriptor/Qualifier:
Bone Transplantation*
Freeze Drying
Humans
Materials Testing
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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