Document Detail

Impact of vitamin D supplementation on markers of bone mineral metabolism in term infants.
MedLine Citation:
PMID:  22776138     Owner:  NLM     Status:  MEDLINE    
CONCLUSIONS: Vitamin D supplements had little to no impact on markers of bone turnover in term infants in the first few months of life, with the exception of osteocalcin. Ten weeks of cholecalciferol supplementation at a dose of 550 IU/day led to a marked increase of 25OHD concentration. The magnitude of 25OHD increment was inversely related to vitamin D status at baseline. Irrespective of the severity of vitamin D deficiency, a secondary hyperparathyroidism with elevated iPTH, ALP, phosphaturia or hypophosphatemia was not observed in the studied neonates.
Justyna Czech-Kowalska; Pawel Pludowski; Anna Dobrzanska; Edyta Kryskiewicz; Elzbieta Karczmarewicz; Dariusz Gruszfeld; Agata Pleskaczynska; Malgorzata Golkowska
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-07-06
Journal Detail:
Title:  Bone     Volume:  51     ISSN:  1873-2763     ISO Abbreviation:  Bone     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-03     Completed Date:  2013-01-28     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8504048     Medline TA:  Bone     Country:  United States    
Other Details:
Languages:  eng     Pagination:  781-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
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MeSH Terms
Biological Markers / metabolism*
Bone Development
Bone and Bones / metabolism*
Dietary Supplements*
Infant, Newborn
Minerals / metabolism*
Vitamin D / administration & dosage*
Reg. No./Substance:
0/Biological Markers; 0/Minerals; 1406-16-2/Vitamin D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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