| Impact of type of atrial fibrillation and repeat catheter ablation on long-term freedom from atrial fibrillation: results from a multicenter study. | |
| | |
MedLine Citation:
|
PMID: 19716348 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
BACKGROUND/OBJECTIVE: The purpose of this prospective multicenter study was to compare results of catheter ablation in patients with paroxysmal atrial fibrillation (PAF) and those with nonparoxysmal atrial fibrillation (NPAF). The impact and the role of repeat catheter ablation were assessed in patients with recurrence. METHODS/RESULTS: One thousand four hundred four patients underwent catheter ablation for atrial fibrillation (AF) performed by 12 operators at four institutions using a single technique guided by intracardiac echocardiography. Of these patients, 728 had PAF and 676 had NPAF. Among the NPAF patients, 293 had persistent AF and 383 had long-standing persistent AF. Patients with NPAF had a higher incidence of hypertension and/or structural heart disease (64.8% vs 48.5%, P = .003) and a lower mean left ventricular ejection fraction (53.3% +/- 8.7% vs 55.7 +/- 6.5%, P <.001). All patients underwent antral isolation of all four pulmonary veins and the superior vena cava. At mean follow-up of 57 +/- 17 months, 565 of 728 patients with PAF and 454 of 676 patients with NPAF (77.6% vs 67.2%, P <.001) had freedom from AF after a single ablation procedure. For arrhythmia recurrences, 74.2% (121/163) patients with PAF and 74.8% (166/222) with NPAF underwent repeat ablation, after which 92.4% patients with PAF and 84.0% patients with NPAF remained free from AF. CONCLUSION: Pulmonary vein antrum isolation guided by intracardiac echocardiography results in significant freedom from AF, even when performed by multiple operators in different centers. At least moderate efficacy can be achieved in patients with NPAF, although the success rate is lower than in patients with PAF. Considerably higher success can be achieved in both groups with repeat ablation. |
| | |
Authors:
|
Mandeep Bhargava; Luigi Di Biase; Prasant Mohanty; Subramanyam Prasad; David O Martin; Michelle Williams-Andrews; Oussama M Wazni; J David Burkhardt; Jennifer E Cummings; Yaariv Khaykin; Atul Verma; Steven Hao; Salwa Beheiry; Richard Hongo; Antonio Rossillo; Antonio Raviele; Aldo Bonso; Sakis Themistoclakis; Kelly Stewart; Walid I Saliba; Robert A Schweikert; Andrea Natale |
Related Documents
:
|
16884508 - The risk profile for obstructive sleep apnea does not affect the recurrence of atrial f... 19404588 - Clinical value of fibrillatory wave amplitude on surface ecg in patients with persisten... 11676038 - The utilisation of a day-surgery unit for direct-current (dc) cardioversion of atrial f... 18174208 - Cardiac injury after percutaneous catheter ablation for atrial fibrillation. 15256188 - Effects of epilepsy on autonomic nervous system and respiratory function tests. 8050728 - Vitamin e supplementation in preeclampsia. |
Publication Detail:
|
Type: Journal Article Date: 2009-06-09 |
Journal Detail:
|
Title: Heart rhythm : the official journal of the Heart Rhythm Society Volume: 6 ISSN: 1556-3871 ISO Abbreviation: Heart Rhythm Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-12-08 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101200317 Medline TA: Heart Rhythm Country: United States |
Other Details:
|
Languages: eng Pagination: 1403-12 Citation Subset: IM |
Affiliation:
|
Cleveland Clinic, Cleveland, OH, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
| Comments/Corrections | |
Comment In:
|
Heart Rhythm. 2009 Oct;6(10):1413-4
[PMID:
19631591
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Conventional versus digital radiographs for intraoperative cervical spine-level localization: a pros...
Next Document: Peripheral relays in stress-induced activation of visceral afferents in the gut.