Document Detail


Impact of temporal resolution on flow quantification by real-time 3D color Doppler echocardiography: numerical modeling and animal validation study.
MedLine Citation:
PMID:  14632016     Owner:  NASA     Status:  MEDLINE    
Abstract/OtherAbstract:
Real-time, 3D color Doppler echocardiography (RT3D) is capable of quantifying flow at the LV outflow tract (LVOT). However, previous works have found significant underestimation for flow rate estimation due to finite scanning time (ST) of the color Doppler. The authors have, therefore, developed a mathematical model to correct the impact of ST on flow quantification and validated it by an animal study. Scanning time to cover the entire cross-sectional image of the LVOT was calculated as 60 ms, and the underestimation due to temporal averaging effect was predicted as 18 +/- 7%. In the animal experiment, peak flow rates were obtained by spatially integrating the velocity data front the cross-sectional color images of the LVOT. By applying a correction factor, there was an excellent agreement between reference flow rate by an electromagnetic flow meter and RT3D (angstroms=-5.6 ml/s, r=0.93), which was significantly better than without correction (p<0.001). Real-time, color 3D echocardiography was capable of quantifying flow accurately by applying the mathematical correction.
Authors:
H Tsujino; M Jones; T Shiota; J X Qin; L A Cardon; A J Morehead; A D Zetts; F Bauer; M Stiges; X Hang; N L Greenberg; J A Panza; J D Thomas
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Computers in cardiology     Volume:  27     ISSN:  0276-6574     ISO Abbreviation:  Comput Cardiol     Publication Date:  2000  
Date Detail:
Created Date:  2003-11-22     Completed Date:  2004-02-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7504430     Medline TA:  Comput Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  761-4     Citation Subset:  S    
Affiliation:
Cardiovascular Imaging Center, The Cleveland Clinic Foundation, Cleveland, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Flow Velocity
Coronary Circulation
Data Interpretation, Statistical
Echocardiography, Doppler, Color*
Echocardiography, Three-Dimensional*
Hemodynamics / physiology
Models, Cardiovascular*
Sheep
Ventricular Function, Left / physiology*
Investigator
Investigator/Affiliation:
J D Thomas / Cleveland Clinic Found, OH

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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