Document Detail

Impact of a standardized hand hygiene program on the incidence of nosocomial infection in very low birth weight infants.
MedLine Citation:
PMID:  18675149     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This study examined the effects of a standardized hand hygiene program on the rate of nosocomial infection (NI) in very low birth weight (VLBW) infants (birth weight < 1500 g) admitted to our neonatal intensive care unit (NICU).
METHODS: We compared the rate of NI in VLBW infants in 2 separate periods. In the first period, staff were encouraged to perform handwashing using a plain fluid detergent (0.5% triclosan). In the second period, a standardized hand hygiene program was implemented using antimicrobial soap (4% chlorhexidine gluconate) and alcohol-based hand rubs.
RESULTS: NI after 72 hours of life was detected in 16 of the 85 VLBW infants in the first period and in 5 of the 80 VLBW infants in the second period. The rate of central venous catheter colonization was significantly lower in the second period (5.8%) than in the first period (16.6%).
CONCLUSION: In our NICU, the incidence of NI in VLBW infants was significantly reduced after the introduction of a standardized handwashing protocol. In our experience, a proper hand hygiene program can save approximately 10 NI episodes/year, at a cost of $10,000 per episode. Therefore, improving hand hygiene practice is a cost-effective program in the NICU.
Maria Grazia Capretti; Fabrizio Sandri; Elisabetta Tridapalli; Silvia Galletti; Elisabetta Petracci; Giacomo Faldella
Related Documents :
18547009 - Care of the infant with inherent metabolic disease.
19598279 - Overexpression of zip-2 mrna in the leukocytes of asthmatic infants.
1003139 - Failure to thrive: a case study in comprehensive care.
19819869 - Implementation of "the consensus statement for the standard of care in spinal muscular ...
11134429 - Economic implications of neonatal intensive care unit collaborative quality improvement.
6690469 - Incidence and origin of clostridium difficile in neonates.
11885709 - Growth of infants during the first 18 months of life in urban and rural areas of southe...
25438389 - Monitoring of congenital anomalies in latvia.
10863659 - Family factors and social support in the developmental outcomes of very low-birth weigh...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of infection control     Volume:  36     ISSN:  1527-3296     ISO Abbreviation:  Am J Infect Control     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-04     Completed Date:  2008-09-30     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  8004854     Medline TA:  Am J Infect Control     Country:  United States    
Other Details:
Languages:  eng     Pagination:  430-5     Citation Subset:  IM    
Department of Preventive Pediatrics and Neonatology, St Orsola-Malpighi General Hospital, University of Bologna, Bologna, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Alcohols / pharmacology
Anti-Infective Agents / pharmacology
Catheterization, Central Venous
Chlorhexidine / analogs & derivatives,  pharmacology
Cross Infection / epidemiology*,  prevention & control*
Equipment and Supplies / microbiology
Hand Disinfection / methods*
Health Personnel
Infant, Newborn
Infant, Very Low Birth Weight
Infection Control / methods*
Intensive Care Units, Neonatal
Soaps / chemistry
Reg. No./Substance:
0/Alcohols; 0/Anti-Infective Agents; 0/Soaps; 55-56-1/Chlorhexidine; MOR84MUD8E/chlorhexidine gluconate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Point-of-use water filtration reduces endemic Pseudomonas aeruginosa infections on a surgical intens...
Next Document:  Varicella zoster virus in health care workers in northern Israel: seroprevalence and predictive valu...